| Abstract:Objective To explore the application value of supraglottic mechanical ventilation via nasopharyngeal airway in endoscopic retrograde cholangiopancreatography (ERCP). Methods Patients who planned to receive ERCP in Linyi People’s Hospital from July to December 2022 were selected as the study objects. Patients eligible for inclusion were stratified and randomized according to whether they were high-risk patients with upper respiratory tract obstruction, and randomly assigned to control group and experimental group at a ratio of 1 : 1, with 64 cases in each group. Patients in experimental group received supraglottic mechanical ventilation via nasopharyngeal airway, while those in control group were given oxygen via nasopharyngeal airway. The differences of pH, arterial partial pressure of carbon dioxide (PaCO2), arterial partial pressure of oxygen (PaO2), lactic acid, blood glucose, percutaneous arterial oxygen saturation (SpO2), hypoxemia and apnea between two groups were compared. Results In experimental group, the decrease of SpO2 was less (P<0.05), and the incidence of perioperative hypoxemia and apnea was lower (P<0.05). The intervention reduced PaCO2 7.8 mmHg 1mmHg=0.133kPa on average in patients at high risk of upper airway obstruction. At the end of operation, the PaO2 in experimental group was higher (P<0.05). There was no significant difference in pH, blood glucose and lactic acid between two groups (P>0.05). Conclusion Supraglottic mechanical ventilation via nasopharyneal airway can reduce the extent of SpO2 decrease following anesthesia induction and the incidence of hypoxemia, it also reduces the number of apnea and increases PaO2 at the end of operation. This approach can enhance perioperative ventilation levels and reduce perioperative CO2 accumulation in patients at high risk of upper airway obstruction. |
